Substituted trifluoropropan-1-yl-imidazole alpha 2-receptor anagonists
AssigneeAdir et Compagnie
InventorsCharles Malen, Guillaume de Nanteuil
Life of this patent
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Abstract
A compound selected from those of formula (I): ##STR1## in which R represents straight-chain or branched lower (C.sub.1 -C.sub.6) alkyl, (C.sub.3 -C.sub.8) cycloalkyl, optionally substituted phenyl, pyridyl or naphthyl, and R.sub.1 and R.sub.2, which are the same or different, each represents hydrogen, straight-chain or branched (C.sub.1 -C.sub.6) alkyl, or straight-chain or branched (C.sub.1 -C.sub.6) acyl, an enantiomer, diastereoisomer and epimer, and an addition salt thereof with a pharmaceutically-acceptable acid. Medicinal product, which is useful as .alpha..sub.2 -antagonist.
Claims9
A compound selected from those of formula (I):
- ##STR11## in which R represents straight-chain or branched lower (C.sub.1 -C.sub.6) alkyl;
- (C.sub.3 -C.sub.8) cycloalkyl;
- phenyl unsubstituted or substituted by one or more halogen atoms by one or more straight-chain or branched (C.sub.1 -C.sub.6) alkyl which alkyl groups are themselves unsubstituted or substituted by one or more halogen atoms or by one or more straight-chain or branched (C.sub.1 -C.sub.6) alkoxyl;
- pyridyl;
- or naphthyl;
- and
- R.sub.1 and R.sub.2, which are the same or different, each represents hydrogen, straight-chain or branched (C.sub.1 -C.sub.6) alkyl, or straight-chain or branched (C.sub.1 -C.sub.6) acyl,
- an enantiomer, diastereoisomer, and epimer, thereof and an addition salt thereof with a pharmaceutically-acceptable acid.
Dependencies are inferred from the claim text.