Column slurry packing compressor
AssigneeHT Chemicals, Inc.
InventorsYehuda Shalon, Tadmor Shalon
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Abstract
A liquid chromatography column that can be rapidly packed without a reservoir column is disclosed. The column includes a double sealed compressor piston with a mixture delivery bore extending through the body of the piston. Resilient sealing means are provided in annular grooves provided in the piston. The piston retains a frit and slurry scraper is mounted to the piston. A method of packing such a column is also disclosed. An outlet end plate including solvent drainage bores is provided. A threaded end cap including radial slots in an inner surface for a threaded column is disclosed, as is an adaptor for joining flanged and threaded columns.
Claims12
A slurry packing compressor for use in a chromatographic column adapted to contain a bed of particles comprising a slurry, said packing compressor comprising:
- a generally cylindrical metallic piston;
- means for receiving resilient means adapted to seal an interface of said chromatographic column and said piston;
- means for enabling material to be separated to be injected into said bed of particles;
- means for dispersing the material to be separated throughout the chromatography column, said dispersing means comprising a plurality of radially extending grooves provided in a slurry facing end surface of said generally cylindrical metallic piston;
- and
- means for retaining a frit comprising a threaded portion, said piston including a threaded portion adjacent the slurry contacting end face of said piston and adapted to engage said threaded portion of said frit retaining means, said frit retaining means further comprising means for receiving a frit sealing means.
Dependencies are inferred from the claim text.