Synthesis of hexahydrolupulone, novel forms thereof, and its use as a selective inhibitor of cell growth and multiplication
AssigneeKalamazoo Holdings, Inc.
InventorsPaul H. Todd, Jr., James A. Guzinski
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Abstract
A process for making hexahydrolupulone is described which involves the separation of beta acids from a hop extract, the removal of catalyst poisons from the beta acids, the hydrogenation of the beta acids to hexahydrolupulone, and the purification of the resulting hexahydrolupulone. Its use as an inhibitor of the growth of unwanted types of cells is described, as well as preferred forms for such use.
Claims2
Stable, essentially pure and instability-inparting-impurity-free hexahydrolupulone, essentially free of impurities at 10.94 and 14.7 minutes, as shown by high performance liquid chromatography at a detection intensity of 355 mm.
Dependencies are inferred from the claim text.