Complexes of saponins and their aglycons with phospholipids and pharmaceutical and cosmetic compositions containing them
AssigneeIndena S.p.A.
InventorsEzio Bombardelli, Gianfranco Patri, Roberto Pozzi
Life of this patent
Estimating the term…
Loading patent…
AssigneeIndena S.p.A.
InventorsEzio Bombardelli, Gianfranco Patri, Roberto Pozzi
Estimating the term…
Complexes of saponins from Centella asiatica, terminalia sp. and Terminalia sericea and relevant aglycons with phospholipids are described. The saponins may be asiaticoside, madecassicoside and sericoside. The molar ratio of phospholipids to saponins is from 0.5 to 2. The phospholipids are selected from the group consisting of soy lecithins, phospholipids from bovine or swine brain or cutis, phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine in which the acyl groups can be the same or different and are mostly derived from palmitic, stearic, oleic, linoleic, linolenic acids. Pharmaceutical compositions and the method of treatment are also described.
A complex of a saponin which is derived from Centella asiatica, Terminalia sp. or Terminalia sericea wherein said saponin is asiaticoside, madecassicoside or sericoside or a mixture thereof with a phospholipid wherein the molar ratio of phospholipid to said saponin is 0.5-2.
Dependencies are inferred from the claim text.