Vaccine for immunizing fish against infectious pancreatic necrosis virus
AssigneeState of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University
InventorJo-ann C. Leong
Life of this patent
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Abstract
A vaccine for simultaneously immunizing large numbers of fish against infection by Infec This invention was made with government support under the following grant numbers awarded by the U.S. Department of Commerce, National Oceanic and Atmospheric Administration, Science and Education Administration: NA81AA-D-00086 (1982-85, Recombinant DNA Technology in Aquaculture, Project No. R/FSD-9, Oregon State University); NA85AA-D-SG-095 (1985-87, Development of a Subunit Vaccine for IPNV, Project No. R/FSD-11, Oregon State University); and NA85AA-D-SG-095 (1987-89, Control of Virus Diseases in Fish, Project No. R/FSD-13, Oregon State University). The government has certain rights in this invention.
Claims9
A method for immunizing fish against the VR-299 and SP serotypes of the infectious pancreatic necrosis virus (IPNV), the method comprising administering to susceptible fish a vaccine comprised of an IPNV polypeptide consisting essentially of a polypeptide from the viral A segment and including at least VP2, the vaccine being administered in an amount sufficient o induce immunity to subsequent infection by IPNV, wherein said polypeptide having been produced in a bacterial host by an expression vector compatible with the host, the expression vector including an inserted DNA sequence from said A segment of the viral DNA coding for the IPNV polypeptide in the vaccine.
A vaccine for immunizing susceptible fish against infection by VR-299 or SP serotypes of the infectious pancreatic necrosis virus (IPNV), the vaccine comprising an IPNV polypeptide consisting essentially of a polypeptide from the viral A segment and including at least VP2, wherein said vaccine is capable of inducing immunity in the fish to subsequent infection by the VR-299 or SP serotypes of IPNV, said polypeptide being produced by an expression vector in a compatible bacterial host, and the vector including an inserted DNA sequence from the A segment of the viral DNA coding for the IPNV polypeptide in the vaccine.
Dependencies are inferred from the claim text.