Implantable glucose sensor
AssigneeUniversity of Kansas
InventorsGeorge S. Wilson, Dilbir S. Bindra, Brian S. Hill, Daniel R. Thevenot, Robert Sternberg, Gerard Reach, Yanan Zhang
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AssigneeUniversity of Kansas
InventorsGeorge S. Wilson, Dilbir S. Bindra, Brian S. Hill, Daniel R. Thevenot, Robert Sternberg, Gerard Reach, Yanan Zhang
Estimating the term…
Implantable enzymatic sensors (25, 43, 44) for biochemicals such as glucose are provided having an ideal size and geometry for optional long term implantation and linear responses over the concentration ranges of interest. The sensors (25, 43, 44) include an elongated body (10, 26, 46) supporting an indicating electrode section having an appropriate enzyme immobilized thereon to present an enzymatic indicating surface (21, 33, 54). A permeable synthetic polymer membrane (24, 42, 56) is applied over the sensor body (10, 26, 46) to protect the enzyme and regulate diffusion of analyte therethrough, to ensure linearity of sensor response. The sensors (25, 43) are of flexible design and can be implanted using a catheter. Alternately, the sensor (44) includes an internal indicating electrode body (46) housed within an apertured, hollow needle (48). A holder (66) affixed to the needle (48) allows for easy manipulation and implantation of the sensor (44).
A sensor adapted for positioning in an environment characterized by the presence of biological molecules which are substrates for or products produced by enzymes in order to determine the presence of said molecules, said sensor comprising:
Dependencies are inferred from the claim text.