Automated synthesizing apparatus

An automated synthesizing apparatus comprising:

• a supply unit which includes a plurality of reservoirs for containing respective raw material, reagents and solvents, volumetric tubes fluidly connected to said plurality of reservoirs for quantification of the raw material, reagents and solvents, said volumetric tubes have gas-liquid boundary sensors thereon, fluid flow lines extending from said plurality of reservoirs and said volumetric tubes for delivery of raw material, reagents and solvents, and a plurality of solenoid valve assemblies disposed on respective said fluid flow lines for selectively opening and closing said fluid flow lines;
• a reaction unit comprising at least one reaction flask device fluidly connected to said fluid flow lines of said supply unit for receiving raw material, reagents and solvents from said supply unit, a separation funnel fluidly connected to said reaction flask device for extracting and washing a reaction liquid transferred from said reaction flask device, a pH adjusting the acidity or basicity of reaction liquid received form said separation funnel, a plurality of additional reagent reservoirs fluidly connected to said reaction flask device for adding a predetermined quantity of reagents to said reaction flask device, a plurality of volumetric tubes for quantification of the reaction liquid and reagents fluidly connected to said reagent reservoirs and said reaction fluidly connected to said reagent reservoirs and said reaction flask device, a plurality of fluid flow lines for delivering the reaction liquid and reagents and solenoid valve assemblies in respective said fluid flow lines for selectively opening and closing said fluid flow lines;
• a purification unit connected to said fluid flow lines of said reaction unit for receiving reaction liquid therefrom and comprising at least one of a high performance liquid chromatography device and a centrifugal partition chromatography device, fluid flow lines for delivering a purified product from said purification unit and solenoid valve assemblies in said fluid flow lines for selectively opening and closing said fluid flow lines;
• a handling unit connected to said fluid flow lines of said purification unit for handling purified products delivered by said purification unit;
• and
• computer control means connected to each of said units, said sensors and said solenoid valve assemblies for controlling the sequence of operation of said units.