Transgultaminase
AssigneesAjinomoto Co., Inc., Amano Pharmaceutical Co., Ltd.
InventorsMasao Motoki, Atsushi Okiyama, Masahiko Nonaka, Haruo Tanaka, Ryosuke Uchio, Akira Matsuura, Hiroyasu Ando, Koichi Umeda
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Abstract
A transglutaminase catalyzing an acyl transfer reaction of a .gamma.-carboxyamide group of a glutamine residue in a peptide or protein chain in the absence of Ca.sup.2+.
Claims6
A transglutaminase which catalyzes an acyl transfer reaction of a .gamma.-carboxyamide group of a glutamine residue in a peptide or protein chain independently of Ca.sup.2+.
A process for producing a transglutaminase, which comprises culturing a microorganism of a strain belonging to the genus Streptoverticillium capable of producing a transglutaminase which catalyzes an acyl transfer reaction of a .gamma.-carboxyamide group of a glutamine residue in a peptide or protein chain independently of Ca.sup.2+, and harvesting said transglutaminase from the culture.
A process for producing a protein gelation product, which comprises contacting a protein-containing solution or slurry having a protein concentration of at least 1.0 wt. % with a transglutaminase which catalyzes an acyl transfer reaction of a .gamma.-carboxyamide group of a glutamine residue in a peptide or protein chain independently of Ca.sup.3+ for a time sufficient to result in gelation of said solution or slurry.
Dependencies are inferred from the claim text.