Plant cells resistant to herbicidal glutamine synthetase inhibitors
AssigneeThe General Hospital Corporation
InventorsHoward M. Goodman, Gunter Donn
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Abstract
A plant cell which is resistant to a herbicidal glutamine synthetase inhibitor, wherein the resistance is caused by levels of GS activity which, when present in an otherwise herbicidal GS inhibitor sensitive plant cell, render the cell substantially resistant to the herbicidal GS-inhibitor.
Claims24
A plant cell which is stably resistant to a herbicidal glutamine synthetase (GS) inhibitor, wherein said resistance is retained in the absence of said inhibitor, wherein said resistance is caused by plant cell levels of GS activity which, when present in an otherwise herbicidal GS-inhibitor sensitive plant cell, render said cell substantially resistant to said herbicidal GS-inhibitor.
A genetic sequence combination operable in a given plant cell which comprises:
- (a) a first genetic sequence coding for glutamine synthetase functional in said plant cell, operably linked to
- (b) a second genetic sequence capable of increasing the levels of expression of said first sequence such that when said combination is present in an otherwise herbicidal GS-inhibitor sensitive plant cell, said cell is substantially resistant to said herbicidal GS-inhibitor.
A method of conferring herbicidal GS-inhibitor resistance to an otherwise herbicidal GS-inhibitor sensitive plant cell which comprises increasing the copies of the naturally occurring GS gene present in said sensitive plant cell.
An isolated DNA molecule comprising a eukaryotic genetic sequence coding for glutamine synthetase wherein said sequence is functional in a plant cell.
An isolated DNA (rDNA) molecule comprising a genetic sequence coding for glutamine synthetase, wherein said glutamine synthetase comprises the following polypeptide formula:
- ##STR6##
Dependencies are inferred from the claim text.