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US 5,144,017 AGranted
Compounds that bind to digitalis receptor
AssigneeUniversity of Manitoba
InventorsFrank S. LaBella, John F. Templeton
Life of this patent
Estimating the term…
Abstract
Novel steroid compounds which are glycoside derivatives of 14.beta.-hydroxypregnane and 17.alpha.-acetoxy-6.alpha.-methylpregnane are described. The compounds have increased receptor potency when compared to their aglycone and beneficial renal effects.
Claims2
A C3-glycoside derivative of a 14.beta.-hydroxypregnane and having the formula:
- ##STR9## wherein GLY is a glycoside radical selected from the group consisting of glucoside, rhamnoside and tridigitoxoside.
A C3-glycoside derivative of a 14.beta.-hydroxypregnane and having the formula:
- ##STR10## where GLY is a glycoside radical selected from the group consisting of glucoside, rhamnoside and tridigitoxoside and R is an amino group.
Dependencies are inferred from the claim text.