Dissolution cell and apparatus for determining solids-dissolving kinetics

A dissolution cell for determining the kinetics of dissolution of a solid substance in a particular liquid, comprising (a) a housing receptacle having a closed bottom end and an open top end, an interior surface of said receptacle defining (i) a lowermost upwardly diverging conical zone provided with liquid inlet means extending from a tip of said control zone through the bottom end of said receptacle, (ii) a first essentially cylindrical zone surmounting said conical zone and (iii) a second essentially cylindrical zone surmounting said first essentially cylindrical zone and having a cross-sectional diameter greater than that of said first essentially cylindrical zone and being in communicating relationship therewith, said conical zone and said first essentially cylindrical zone defining a chamber for the dissolution of a solid substance in a liquid solvent, a solid substance disposed in said chamber, (b) means flowing a liquid solvent into and through said cell, (c) a closure leakproofedly secured to the open end of said receptacle and provided with solute outlet means, and (d) filtration means arranged to engage said interior surface of said receptacle at a region of communicating relationship between said first and said second essentially cylindrical zones, so as to be disposed in a pathway for the solute extending from said dissolution chamber to said solute outlet means, said closure including means engaging said filtration means to maintain said filtration means in engagement with said interior surface of said receptacle.