US 5,142,056 A · Retroviral protease inhibiting compounds

Abstract

A retroviral protease inhibiting compound of the formula A--X--B or a pharmaceutically acceptable salt, prodrug or ester thereof, wherein X is a linking group; A is (1) substituted amino, (2) substituted carbonyl, (3) functionalized imino, (4) functionalized alkyl, (5) functionalized acyl, (6) functionalized heterocyclic or (7) functionalized (heterocyclic)alkyl; and B is (1) substituted carbonyl independently defined as herein, (2) substituted amino independently defined as herein, (3) functionalized imino independently defined as herein, (4) functionalized alkyl independently defined as herein, (5) functionalized acyl independently defined as herein, (6) functionalized heterocyclic independently defined as herein or (7) functionalized (heterocyclic)alkyl independently defined as herein.

Claims5

Dependent claims

A compound of the formula:

##STR523## wherein R.sub.17 is 2-pyridinylmethyl, 3-pyridinylmethyl or 4-pyridinylmethyl and R.sub.800 is --O-- or --N(CH.sub.3)--;
or a pharmaceutically acceptable salt, prodrug or ester thereof.

Dependencies are inferred from the claim text.

Facts

Application

07/518,730Filed 9 May 1990 · continuation in part

Priority

23 May 1989

Granted

25 Aug 1992

Term ends

Not estimatedThe source records don’t support an estimate.

Classification113 codes

C07D 207/08
Having no double bonds between ring members or between ring members and non-ring members: with hydrocarbon radicals, substituted by hetero atoms,…
A61P 31/12
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antivirals
A61P 37/04
Immunomodulators: immunostimulants
C07C 33/46
Halogenated unsaturated alcohols: containing only six-membered aromatic rings as cyclic parts

Retroviral protease inhibiting compounds

Life of this patent

Retroviral protease inhibiting compounds

Life of this patent

Abstract

Claims5