Sterile entry/exit total containment process for closed systems using plastic tubes
AssigneeDenco, Inc.
InventorsJohn B. Shaposka, Dudley W. Spencer
Life of this patent
Estimating the term…
Abstract
A process for sterile entry/exit into a closed system permits safe addition of reagent/nutrient/process modules, etc., removal of biological samples or depleted process modules such as filters, etc. all without exposing the operator to possibly dangerous materials such as blood and without endangering the contents of the system such as in cell-culturing. A novel welder and process is disclosed to illustrate the process.
Claims10
A device for welding/sealing plastic tubes comprising a pair of side by side clamping assemblies, each of said clamping assemblies including a longitudinal holder having at least two tube receiving grooves extending across said holder, each of said grooves in said holders being alignable with a corresponding groove in the other of aid holders, means for longitudinally moving one of said holders to realign said grooves with respect to each other, means for laterally moving at least one of said holders toward the other of said holders, a heatable wafer generally disposed in a gap between said holders and mounted for reciprocating movement up and down in a vertical plane into and out of said gap, each of said clamping assemblies including a clamping member hingedly mounted over its respective holder and selectively lockably engaged with its said holder for clamping the tubes in said grooves, and a heater mounted longitudinally on each side of said wafer.
A device for welding plastic tubes comprising three side by side clamping assemblies which consist of two end assemblies and a central assembly, each of said assemblies including a holder having a pair of tube receiving grooves, said central assembly being longitudinally movable into alignment with said end assemblies and completely out of alignment with said end assemblies, at least one of said end assemblies being laterally movable toward the other end assembly whereby tube sections in said end assemblies may contact each other when said central assembly is moved out of alignment therewith, and heatable wafer means being movable into a gap between each pair of side by side assemblies.
A device for welding/sealing plastic tubes comprising a pair of side by side clamping assemblies, each of said clamping assemblies including a circular disk having at least two tube receiving groove extending across the periphery of said disk, each of said grooves in said disks being alignable with a corresponding groove in the other of said disks, one of said disks being rotatable to realign said grooves with respect to each other, one of said disks being laterally movable toward the other of said disk, and a heatable wafer generally in a gap between said disks and mounted for reciprocating movement into and out of said gap.
Dependencies are inferred from the claim text.