Composite material having absorbable and non-absorbable components for use with mammalian tissue
AssigneeAmerican Cyanamid Company
InventorHenry P. Landi
Life of this patent
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Abstract
The invention is a composite material of two or more biocompatible polymers, at least one of which is polytetrafluoroethylene (PTFE) and one of which is a bioabsorbable polymer. The nonabsorbable PTFE is used in the composite as a reinforcing binder. The reinforcing binder is a network of unsintered, interconnected micro-fibers which are formed, for example, by blending with a thermoplastic polymer vehicle, such as polymethylmethacrylate which is subsequently extracted. The bioabsorbable component is contained within the structure of the PTFE microfibrils. This composite is useful in the repair of mammalian tissue where tissue ingrowth and permenant support is required.
Claims20
A composite material for use with mammalian tissue consisting essentially of:
- (a) an unsintered, microfibrillar, non-absorbable biocompatible component prepared from polytetrafluoroethylene,
- (b) a particulate bioabsorbale filler manufactured from a polymer prepared from one or more monomers selected from the group consisting of lactides, carbonates, oxalates and lactones, and
- (c) a non-absorbable, biocompatible thermoplastic component manufactured from a polymer which is liquid at a temperature from about 150.degree. to 200.degree. C. and solid at ambient temperature, and which provides additional integrity to the unsintered component.
A composite material for use with mammalian tissue consisting essentially of:
- (a) an unsintered, microfibrillar, non-absorbable biocompatible component prepared from polytetrafluoroethylene,
- (b) a micropulverized bioabsorbable powder manufactured from a polymer prepared from one or more monomers selected from the group consisting of lactides, carbonates, oxalates and lactones, and
- (c) a non-absorbable, biocompatible thermoplastic component manufactured from a polymer which is liquid at a temperature from about 150.degree. to 200.degree. C. and solid at ambient temperature, and which provides additional integrity to the unsintered component.
A composite material for use with mammalian tissue consisting essentially of:
- (a) an unsintered, microfibrillar, non-absorbable biocompatible component prepared from polytetrafluoroethylene, and
- (b) a bioabsorbable powder manufactured from a polymer prepared from one or more monomers selected from the group consisting of lactides, carbonates, oxalates and lactones, and optionally
- (c) a non-absorbable, biocompatible thermoplastic component manufactured from a polymer which is liquid at a temperature from about 150.degree. to 200.degree. C. and solid at ambient temperatures, and which provides additional integrity to the unsintered component.
Dependencies are inferred from the claim text.