Single-needle type plasma separation apparatus and plasma collection apparatus

A plasma collection apparatus to which is connected a blood separation circuit comprising:

• a blood collection needle;
• a blood collection container;
• a first blood transportation tube connecting said blood collection needle to said blood collection container;
• a plasma separator;
• a second blood transportation tube connecting said blood collection container to a blood inlet of said blood separator;
• a third blood transportation tube connecting a blood outlet of said plasma separator to said first blood transportation tube;
• a plasma collection container;
• and a plasma transportation tube connecting a plasma outlet of said plasma separator to said plasma collection container;
• a receptacle accommodating said blood collection container in its interior;
• pressurizing means for pressurizing or depressurizing the interior of said receptacle;
• first shut-off means for closing said first blood transportation tube of said blood separation circuit;
• second shut-off means for closing said second or third blood transportation tube thereof;
• and third shut-off means for closing said plasma transportation tube thereof;
• and
• control means for actuating said pressurizing means to depressurize the interior of said receptacle to transport blood into said blood collection container through said first blood transportation tube, and for pressurizing the interior of said receptacle to transport blood into said plasma separator from said blood collection container.

A plasma collection apparatus to which is connected a blood separation circuit comprising:

• a blood collection needle;
• a blood collection container containing an anticoagulant liquid;
• a first blood transportation tube connecting said blood collection needle to said blood collection container;
• a plasma separator;
• a second blood transportation tube connecting said blood collection container to a blood inlet of said plasma separator;
• a third blood transportation tube connecting a blood outlet of said plasma separator to said first blood transportation tube;
• a plasma collection container;
• and a plasma transportation tube connecting a plasma outlet of said plasma separator to said plasma collection container;
• a receptacle accommodating said blood collection container in its interior;
• pressurizing means for pressurizing or depressurizing the interior of said receptacle;
• first shut-off means for closing said first blood transportation tube of said blood separation circuit;
• second shut-off means for closing said second blood transportation tube thereof;
• and third shut-off means for closing said plasma transportation tube thereof;
• control means for (a) carrying out a blood collection step by actuating said pressurizing means to depressurize the interior of said receptacle so as to collect a predetermined amount of blood into said blood collection container from a donor, (b) carrying out a small amount blood return step by actuating said pressurizing means to pressurize the interior of said receptacle after completion of said blood collection step so as to return blood remaining in said first blood transportation tube to said donor and flow the blood collected in said blood collection container, and to which said anticoagulant liquid has been added, into said first blood transportation tube, and (c) a carrying out a separation and blood return step by actuating said pressurizing means to pressurize the interior of said receptacle after completion of said small amount blood return step so as to flow the blood collected in said blood collection container into said plasma separate, collect a plasma component into said plasma collection container from said plasma outlet of said plasma separator, and return a red blood cell component to said donor from the blood cell outlet of said plasma separator.

A plasma collection apparatus to which is connected a blood separation circuit comprising:

• a blood collection needle;
• a blood collection container;
• a first blood transportation tube connecting said blood collection needle to said blood collection container;
• a plasma separator;
• a second blood transportation tube connecting said blood collection container to a blood inlet of said plasma separator;
• a third blood transportation tube connecting a blood outlet of said plasma separator to said first blood transportation tube;
• a plasma collection container;
• a plasma transportation tube connecting a plasma outlet of said plasma separator to said plasma collection container;
• an anticoagulant liquid container;
• and an anticoagulant liquid transportation tube connecting said anticoagulant liquid container to said blood collection container;
• a receptacle accommodating said blood collection container in its interior;
• pressurizing means for pressurizing or depressurizing the interior of said receptacle;
• first shut-off means for closing said first blood transportation tube of said blood separation circuit;
• second shut-off means for closing said second blood transportation tube;
• third shut-off means for closing said plasma transportation tube;
• and fourth shut-off means for closing said anticoagulant liquid transportation tube;
• control means for (a) carrying out an anticoagulant liquid injection step by actuating said pressurizing means to depressurize the receptacle so as to inject a predetermined amount of anticoagulant liquid into said blood collection container from said anticoagulant liquid container, (b) carrying out a blood collection step by actuating said pressurizing means to depressurize said receptacle after completion of said anticoagulant liquid injection step so as to collect a predetermined amount of blood into said blood collection container from a donor (c) carrying out a small amount blood return step by actuating said pressurizing means to pressurize said receptacle after completion of said blood collection step so as to return blood remaining in said first blood transportation tube to said donor and flow the blood collected in said blood collection container, and to which said anticoagulant liquid has been added, into said first blood transportation tube, and (d) carrying out a separation and blood return step by actuating said pressurizing means to pressurize the receptacle after completion of said small amount blood return step so as to flow the blood collected in said blood collection container into said plasma separator, collect a plasma component into said plasma collection container from said plasma outlet of said plasma separator, and return a red blood cell component to said donor from the blood cell outlet of said plasma separator.