.alpha.-Glycosyl-L-ascorbic acid, and its preparation and uses
AssigneeKabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
InventorsItaru Yamamoto, Norio Muto, Toshio Miyake
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Abstract
.alpha.-Glycosyl-L-ascorbic acid exhibiting no direct reducing activity is formed in a solution containing L-ascorbic acid and an .alpha.-glucosyl saccharide when subjected to the action of a saccharide-transferring enzyme. .alpha.-Glycosyl-L-ascorbic acid is superiorly stable, and readily hydrolyzable in vivo to exhibit the activities inherent to L-ascorbic acid. Thus, .alpha.-glycosyl-L-ascorbic acid is favorably useful as a stabilizer, quality-improving agent, antioxidant, physiologically active agent and uv-absorbent in food pharmaceutical and cosmetic industries.
Claims10
An .alpha.-glycosyl-L-ascorbic acid of the formula:
- ##STR5## wherein n is an integer of 0 to 6.
A stable .alpha.-glycosyl-L-ascorbic acid made by the process of claim 3, said ascorbic acid exhibiting no direct reducing activity.
A process for preparing an .alpha.-glycosyl-L-ascorbic acid exhibiting no direct reducing activity, comprising:
- providing a solution which contains at least 1 w/v % L-ascorbic acid and an .alpha.-glycosyl saccharide in an amount of 0.5-to 30-fold higher than that of the L-ascorbic acid;
- applying a saccharide-transferring enzyme to the solution containing said L-ascorbic acid and said .alpha.-glucosyl saccharide at a pH in the range of 3-9, and permitting said enzyme to act on said L-ascorbic acid and saccharide to form an .alpha.-glycosyl-L-ascorbic acid exhibiting no direct reducing activity;
- and
- recovering the .alpha.-glycosyl-L-ascorbic acid.
Dependencies are inferred from the claim text.