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US 5,136,080 AGranted
Nitrile compounds
AssigneeBurroughs Wellcome Co.
InventorsAlistair A. Miller, Malcolm S. Nobbs, Richard M. Hyde, Michael John
Life of this patent
Estimating the term…
Abstract
A class of substituted phenylpyrimidine compounds are disclosed which are potent inhibitors of the excitatory amino acid, glutamate. Such compounds are useful in the treatment or prevention of a range of CNS disorders including cerebral ischaemic damage and epilepsy.
Claims4
A compound selected from the group
- 2-(2,3,5-trichlorophenyl)-4,4,4-trifluoro-3-methoxybut-2-enonitrile;
- 2-(2,3,5-trichlorophenyl)-4-methoxy-3-oxobutyronitrile;
- or
- 2-(2,3,5-trichlorophenyl)-3-methoxy-acrylonitrile.
1 more element
The compound 2-(2,3,5-trichlorophenyl)-4,4,4-trifluoro-3-methoxybut-2-enonitrile.
The compound 2-(2,3,5-trichlorophenyl)-4-methoxy-3-oxobutyronitrile.
The compound 2-(2,3,5-trichlorophenyl)-3-methoxy-acrylonitrile.
Dependencies are inferred from the claim text.