Method of localizing and quantifying regional energy metabolism in a warm-blooded living being and composition therefor
AssigneeMallinckrodt Medical, Inc.
InventorJurgen Schrader
Life of this patent
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Abstract
The invention relates to a method of localizing and quantifying regional energy metabolism, in particular regional ischemia, in a warm-blooded living being, comprising administering to said being a diagonstically effective quantity of a radiolabelled L-homocysteine or a radiolabelled functional derivative thereof. The invention further relates to a pharmaceutical composition to be used for performing the above method.
Claims11
A method of localizing and quantifying regional energy metabolism in a warm-blooded living being, comprising:
- (a) administering to said being a diagnostically effective quantity of a radiolabelled L-homocysteine which has been radiolabelled with a radioisotope capable of emitting positron or gamma radiation;
- and
- (b) detecting positron or gamma radiation emissions from the radiolabelled L-homocysteine administered to said being, such that regional energy metabolism in the being is localized and quantified.
A pharmaceutical composition for localizing and quantifying regional energy metabolism such as regional ischemia comprising:
- a pharmaceutically acceptable carrier and, optionally, at least one pharmaceutically acceptable adjuvant;
- and
- an active substance comprising a diagnostically effective quantity of a radiolabelled L-homocysteine which has been radiolabelled with a radioisotope capable of emitting positron or gamma radiation.
Dependencies are inferred from the claim text.