Use of a statin derivative in the treatment of eye complaints
AssigneeSanofi
InventorsDino Nisato, Gerard Le Fur
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Abstract
The invention relates to the use of N-(3-pyridylpropionyl)phenylalanylhistidyl (cyclohexyl)statyl-N-(1,3-dihydroxy-2-methylpropyl)isoleucinamide, which has the formula ##STR1## in which: Phe is the (L)-phenylalanine residue, His is the (L)-histidine residue, Ile is the (L)-isoleucine residue and (cyclohexyl)Sta is the cyclohexylstatin residue, i.e. the (3S, 4S)-4-amino-5-cyclohexyl-3-hydroxypentanoic acid residue, for the preparation of drugs useful in the treatment of eye complaints. Application: treatment of eye complaints.
Claims10
A method of treatment of glaucoma which comprises administering to a subject suffering from glaucoma a drug comprising an effective amount of the compound N-(3-pyridylpropionyl)phenylalanylhistidyl-(cyclohexyl)statyl-N-(1,3-dihyd roxy-2-methylpropyl)isoleucinamide.
A method of treatment of diabetic retinopathy which comprises administering to a subject suffering from glaucoma a drug comprising an effective amount of the compound N-(3-pyridylpropionyl)phenylalanylhistidyl-(cyclohexyl)statyl-N-(1,3-dihyd roxy-2-methylpropyl)isoleucinamide.
Dependencies are inferred from the claim text.