US 5,132,459 AGranted

Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals

AssigneeSandoz Ltd.

InventorAnton Stuetz

Life of this patent

Estimating the term…

Compounds of formula I ##STR1## wherein R.sub.1 represents a group of formula ##STR2##

Dependent claims

A compound in trans configuration of the formula:

##STR85## wherein R.sub.1 is a radical of formula IIa, ##STR86## R.sub.2, R.sub.3, R.sub.5, and R.sub.8 are each hydrogen, R.sub.4 is methyl, and
R.sub.6 is a radical of formula IIIa
--C.tbd.C--R.sub.11 IIIa
where R.sub.11 is alkyl of 2 to 6 carbon atoms or a chemotherapeutically acceptable acid addition salt thereof.

1 more element

Dependencies are inferred from the claim text.

C07D 333/58
With only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring: radicals…
C07C 33/048
Acyclic alcohols with carbon-to-carbon triple bonds: with double and triple bonds
C07C 33/12
Alcohols containing rings other than six-membered aromatic rings: containing five-membered rings
C07D 211/12
With radicals containing only carbon and hydrogen atoms attached to ring carbon atoms: with only hydrogen atoms attached to the ring nitrogen atom

From the US filing history. Foreign family members aren’t listed.

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Facts

Application

07/384,237Filed 21 Jul 1989 · continuation

Priority

21 Aug 1980

Granted

21 Jul 1992

Term ends

Not estimatedThe source records don’t support an estimate.

C07D 333/58
With only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring: radicals…
C07C 33/048
Acyclic alcohols with carbon-to-carbon triple bonds: with double and triple bonds
C07C 33/12
Alcohols containing rings other than six-membered aromatic rings: containing five-membered rings
C07D 211/12
With radicals containing only carbon and hydrogen atoms attached to ring carbon atoms: with only hydrogen atoms attached to the ring nitrogen atom

Family

Serial180,207Parent of this continuation-in-part · filed 21 Aug 1980

Serial233,559Parent of this continuation · filed 11 Feb 1981

Serial646,724Parent of this division · filed 4 Sep 1984

Serial209,747Parent of this continuation · filed 21 Jun 1988

US 4,755,534 AParent of this division

US 5,132,459 AThis patent

From the US filing history. Foreign family members aren’t listed.