Method for inhibiting production of IGE and method for enhancing production of IGG using interleukin 9 and inhibitors thereof
AssigneesLudwig Institute for Cancer Research, Departemente d'Immunologie Institut Henri Beaufour
InventorsBernard Dugas, Catherine Druez, Pierre Braquet, Jean M. Mencia-Huerta, Catherine Uyttenhove, Jean-Christophe Renauld, Jacques Van Snick
Life of this patent
Estimating the term…
Abstract
A method for inhibiting production of IgE, and a method for enhancing production of IgG are taught. The methods are linked to the role of interleukin 9 in antibody production. Specifically, production of IgG is potentiated by administering either to a subject or a cell culture a combination of interleukin 4 and interleukin 9. Production of IgE is inhibited by administering an amount of an interleukin 9 inhibitor to a subject.
Claims2
Method for enhancing production of IgG in a subject comprising administering to said subject an IgG production enhancing amount of a combination of interleukin 4 and interleukin 9.
Method for enhancing production of IgG in a culture of IgG producing cells comprising administering to said cell culture a combination of interleukin 4 and interleukin 9 in an amount sufficient to enhance IgG production of said cell culture.
Dependencies are inferred from the claim text.