US 5,132,097 A · Apparatus for analysis of specific binding complexes

Abstract

A system for analysis of specific binding complexes. A reaction surface is treated with a specific receptor chemical (SRC) having specific binding properties and is allowed to bind with an unknown reactant to form specific binding complexes (SRC) on the reaction surface. The output of a laser is directed through the reaction surface to a detection mechanism. Shadows in the detected light may be interpreted to detect the presence of the unknown reactant. The unknown reactant may also be quantified. Preferred embodiments of apparatus, and methods of their use, are disclosed for detecting the presence of the unknown reactant within a system for interpreting the results, including interactive system components by which the bases for interpretation may be updated.

Claims2

Dependent claims

A detection system for use during analysis of a specific binding complex, the specific binding complex being carried on a reaction surface of a substrate, the detection system comprising:

a source of analytical radiation;
means directing said analytical radiation through said substrate reaction surface while causing said analytical radiation to converge at said reaction surface;
semiconductor means responsive to the analytical radiation passing through said reaction surface for providing a signal representative thereof;
and
means for processing said signal.

2 more elements

Dependencies are inferred from the claim text.

Apparatus for analysis of specific binding complexes

Life of this patent

Apparatus for analysis of specific binding complexes

Life of this patent

Abstract

Claims2