Serotonin antagonists, their preparation and medications containing them

A compound of the formula:

• ##STR9## in which R.sub.1 denotes
• a 1,2,3,6-tetrahydro-1-pyridyl radical substituted in the 4- position by (a) a phenyl radical, (b) a phenyl radical substituted by a halogen atom or an alkyl, hydroxyl or alkoxy radical, (c) a 3-indolyl radical, (d) a 3-indolyl radical substituted on the nitrogen atom by an alkyl or alkylcarbonyl radical and/or in the 5- position by a chlorine or fluorine atom or (e) a 3-(5-hydroxyindolyl) radical,
• a 1-piperazinyl radical substituted in the 4-position by (a) a phenyl radical, (b) a phenyl
• radical substituted by an alkoxy, alkyl, hydroxyl, nitro or amino radical or a halogen atom, (c) a 1,2-benzisothiazol-3-yl radical, (d) a 1,2-benzisoxazol-3-yl radical or (e) a 2-pyridyl radical, a piperidino radical substituted in the 4- position by (a) a phenyl radical, (b) a phenyl radical substituted by a halogen atom or a hydroxyl, alkyl or alkoxy radical, (c) two phenyl radicals, (d) a bis(4-fluorophenyl)methylene radical, (e) a 4-fluorobenzoyl radical, (f) a 2-oxo-1-benzimidazolinyl radical, (g) a 2-oxo-1-benzimidazolinyl radical substituted in the 3-position by an alkylcarbonyl or benzoyl radical, (h) a hydroxyl radical and a phenyl radical optionally substituted by an alkyl, alkoxy or hydroxyl radical or a halogen atom, (i) a 3-indolyl radical, (j) a 3-indolyl radical substituted on the nitrogen atom by an alkyl or alkylcarbonyl radical and/or in the 5-position by a chlorine or fluorine atom or (k) a 3-(5-hydroxyindolyl) radical,
• n is equal to 2, 3 or 4,
• and their salts with inorganic or organic acids, it being understood that the alkyl and alkoxy radicals or the alkyl parts contain from 1 to 4 carbon atoms as a straight or branched chain.