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US 5,128,171 AGranted
Method of making a test strip having a dialyzed polymer layer
AssigneePolymer Technology International Corp.
InventorJohn M. Gleisner
Life of this patent
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Abstract
A test strip for the detection of a predetermined substance in a fluid is described. This test strip is stable to storage and accelerated keeping test conditions and comprises a support having thereof a reagent layer wherein the reagent layer contains a dialyzed latex polymer and a reagent detection system which reacts with the substance to provide a detectable change.
Claims9
A method for making a test strip for the detection of a predetermined substance, the method comprising:
- dialyzing a predetermined amount of latex polymer to permit low molecular weight species, unreacted monomer, catalyst, and surfactant to pass through a dialysis membrane to provide a dialyzed latex polymer;
- mixing the dialyzed latex polymer with a reagent detection system for detecting the predetermined substance wherein the dialyzed latex polymer constitutes at least 60% by weight of the dry mixture;
- coating the mixture on a support;
- heating the coating support to form a dry reagent layer;
- and cutting the coated support into strips of the desired size.
2 more elements
A method for making a test strip for the detection of glucose, the method comprising:
- dialyzing a predetermined amount of carboxylated vinylacetate/ethylene copolymer;
- mixing the dialyzed copolymer with glucose oxidase, peroxidase, and a color indicator that changes color when the mixture is exposed to glucose, the mixture constituting at least 60% dialyzed copolymer by weight of the dry mixture;
- coating the mixture on a support;
- heating the coated support to form a dry reagent layer;
- and
- cutting the coated support into strips of the desired size.
3 more elements
Dependencies are inferred from the claim text.