Mixture of a positive and negative contrast agent for magnetic resonance imaging
AssigneeNYCOMED GmbH
InventorsArne Berg, Jo Klaveness
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Abstract
There is provided a method of generating enhanced images of the human or non-human animal body, for example for use in medical diagnosis, which involves administering to the body a positive MRI contrast agent which is body tissue- or body duct-specific following the particular mode of administration and a negative MRI contrast agent which preferably also is body tissue- or body duct-specific. Thereafter a magnetic resonance image is generated of a part of the body containing the negative and positive contrast agents or their paramagnetic, ferromagnetic or superparamagnetic biodegradation products. Contrast media suitable for use in this new image generating method are also provided.
Claims17
A magnetic resonance imaging contrast medium comprising at least one physiologically acceptable body tissue- or body duct-specific negative MRI contrast agent together with at least one physiologically acceptable body tissue- or body duct-specific positive MRI contrast agent.
A MRI contrast medium kit comprising a first container containing a negative MRI contrast medium in an administration form adapted for body tissue- or body duct-specific contrast enhancement and a second container separately containing a positive MRI contrast medium in an administration form adapted for body tissue- or body duct-specific contrast enhancement.
A method of generating images of the human or non-human animal body, which method comprises administering to said body a diagnostically effective amount of a body tissue- or body duct-specific MRI contrast agent and of a body tissue- or body duct-specific positive MRI contrast agent and generating a magnetic resonance image of a part of said body containing said negative and positive agents or paramagnetic, ferromagnetic, or superparamagnetic biodegradation products thereof.
Dependencies are inferred from the claim text.