Vitamin A aerosol-inhalate preparations

A pharmaceutical preparation according to claim 2 in which said active substance is a member selected form the group consisting of esters of retinol with physiologically compatible carboxylic acids and esters of retinoic acid with alcohols.

An aerosol-inhalate pharmaceutical preparation comprising 0.01% to 50% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, the aerosol-inhalate in the form of a mist aerosol, said preparation further comprising 0% to 49.99% by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent and 50% to 99.99% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.01% to 30% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, the aerosol-inhalate being a mist aerosol, said preparation further comprising 0% to 30% by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent, and 40% to 99.99% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.05% to 25% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, said aerosol-inhalate in the form of a mist aerosol, said preparation further comprising 0% to 30% by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent, and 45% to 99.99% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.1% to 15% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, the aerosol-inhalate in the form of a mist aerosol, said preparation further comprising 0% to 25% by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent and 60% to 99.99% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.1% to 10% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, said aerosol-inhalate in the form of a mist aerosol, said preparation further comprising 0% to 25% by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent, and 65% to 99.99% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.1% to 7% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, said aerosol-inhalate in the form of a mist aerosol, said preparation further comprising 5% to 23% by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent, and 70% to 94.9% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.1% to 5% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, said aerosol-inhalate in the form of a mist aerosol, said preparation further comprising 10% to 20% by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent, and 75% to 89.9% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.17% by weight retinol palmitate, said preparation in the form of a mist-aerosol, said preparation further comprising 19.83% by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent, and 80% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 3.9% by weight retinol palmitate, said aerosol-inhalate in the form of a mist-aerosol, said preparation further comprising 20 by weight of a non-aqueous lipophilic readily volatile and physiologically compatible solvent, and 76.1% by weight of a propellant gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.01% to 50% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, said aerosol-inhalate in the form of a mist-aerosol, said preparation further comprising 1% to 30% by weight of an emulsifier and/or water-miscible, physiologically compatible liquid, the balance comprised of water and carrier gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.05% to 20% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, said aerosol-inhalate in the form of a mist-aerosol, said preparation further comprising 5% to 30% by weight of an emulsifier and/or water-miscible, physiologically compatible solvent, the balance comprised of water and carrier gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.01% to 10% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, said aerosol-inhalate in the form of a mist-aerosol, said preparation further comprising 5% to 25% by weight of an emulsifier and/or water-miscible, physiologically compatible liquid, the balance comprised of water and carrier gas.

An aerosol-inhalate pharmaceutical preparation comprising 0.05% to 5% by weight of at least one active substance selected from the group consisting of an ester of retinol and an ester of retinoic acid, said aerosol-inhalate in the form of a mist-aerosol, said preparation further comprising 10% to 25% by weight of an emulsifier and/or water-miscible, physiologically compatible liquid, the balance comprised of water and carrier gas.

An aerosol-inhalate pharmaceutical preparation comprising retinol palmitate oil (1 million Iu/g) at 1.0% by weight stabilized with BHA/BHT, said preparation further comprising 22.0% by weight of an emulsifier, 2.0% by weight 1,2-propylene glycol, the balance comprised of water and carrier gas.