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US 5,106,748 AGranted
DNA sequences encoding 5 proteins
AssigneeGenetics Institute, Inc.
InventorsJohn M. Wozney, Vicki A. Rosen, Elizabeth A. Wang
Life of this patent
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Abstract
Purified BMP-5 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
Claims4
An isolated DNA molecule having a sequence encoding a BMP-5 protein which is characterized by the ability to induce the formation of cartilage and/or bone said DNA comprising the DNA sequence selected from the group consisting of
- (a) nucleotide #1 to #102 of FIG. 3;
- (b) nucleotide #1665 to #2060 of FIG. 4;
- (c) nucleotide #699 to #2060 of FIG. 4;
- and
- (d) naturally occurring allelic sequences and equivalent degenerative condon sequences of (a), (b), and (c).
2 more elements
Dependencies are inferred from the claim text.