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US 5,100,792 AGranted
Method for transporting substances into living cells and tissues
AssigneeCornell Research Foundation, Inc.
InventorsJohn C. Sanford, Edward D. Wolf, Nelson K. Allen
Life of this patent
Estimating the term…
Abstract
Inert or biologically active particles are propelled at cell at a speed whereby the particles penetrate the surface of the cells and become incorporated into the interior of the cells. The process can be used to mark cells or tissue or to biochemically affect tissues or tissue in situ as well as single cells in vitro. Apparatus for propelling the particles toward target cells or tissues are also disclosed. A method for releasing particles adhered to a rotor device is also disclosed.
Claims18
A method for introducing particles into at least one living cell comprising:
- positioning the particles to be accelerated, the particles having a diameter sufficiently small to penetrate said at least one cell without killing the cell, and
- accelerating the particles to thereby penetrate the surface of and become incorporated into the interior of said at least one cell.
Dependencies are inferred from the claim text.