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US 5,100,564 AGranted
Blood collection and processing system
AssigneePall Corporation
InventorsDavid B. Pall, Thomas C. Gsell
Life of this patent
Estimating the term…
Abstract
A system for collecting and processing donated blood comprises a first porous medium interposed between a blood collection bag and a satellite bag and a second porous medium interposed between the blood collection bag and another satellite bag. The porous media are leucocyte depletion media. The system can be used to centrifuge whole blood into one or more components, and a means for protecting the system during centrifugation including a bracket carried by the centrifuge bucket for receiving the porous media.
Claims123
A blood collection and processing system comprising
- a first container;
- a second container in fluid communication with the first container;
- a third container in fluid communication with the first container;
- a first porous medium interposed between the first container and the second container comprising at least one of a leucocyte depletion medium, a red cell barrier medium, and a combined leucocyte depletion red cell barrier medium;
- and
- a second porous medium interposed between the first container and the third container and comprising a leucocyte depletion medium.
3 more elements
A blood collection and processing system comprising:
- a bucket;
- at least one container fitted in the bucket;
- at least one filter assembly in fluid communication with the container;
- and
- a bracket receiving the filter assembly and carried by the bucket.
2 more elements
A blood centrifugation and processing system comprising:
- a centrifuge having at least two buckets;
- at least one container which fits in a bucket;
- at least one filter assembly in fluid communication with the container;
- and
- a bracket adapted to receive the filter assembly and carried by at least one of said buckets.
2 more elements
A blood collection and processing system comprising:
- a first container;
- a second container in fluid communication with the first container;
- a third container in fluid communication with the first container;
- a first porous fibrous medium interposed between the first container and the second container comprising at least one of a leucocyte depletion medium, a red cell barrier medium, and a combined leucocyte depletion and red cell barrier medium;
- and
- a second porous fibrous medium interposed between the first container and the third container and comprising a leucocyte depletion medium;
- the first and second porous media having fibers which have been modified to present hydroxyl groups.
4 more elements
A blood collection and processing system comprising
- a blood collection bag;
- a first satellite bag;
- a second satellite bag;
- tubing connecting the blood collection bag to the first satellite bag and to the second satellite bag;
- a first porous medium interposed in the tubing between the collection bag and the first satellite bag comprising at least one of a leucocyte depletion medium, a red cell barrier medium, and a combined leucocyte depletion red cell barrier
- medium;
- said first porous medium having a zeta potential of about -3 to about -30 millivolts at pH of 7.3 and a CWST of greater than about 70 dynes/cm;
- and
- a second porous medium interposed in the tubing between the collection bag and the second satellite bag and comprising a leucocyte depletion medium, said second porous medium having a CWST of greater than about 53 dynes/cm, a voids volume of about 60% to about 90%, and a flow area of about 30 to about 60 cm.sup.2.
6 more elements
A method for collecting and processing blood comprising:
- collecting whole blood in a container;
- centrifuging the whole blood;
- passing the supernatant layer of the centrifuged blood through a first porous medium, the first porous medium comprising at least one of a leucocyte depletion medium, a red cell barrier medium, and a combined leucocyte depletion red cell barrier medium;
- and
- passing the sediment layer of the centrifuged blood through a second porous medium, the second porous medium comprising a leucocyte depletion medium.
2 more elements
A method for collecting and processing blood comprising:
- collecting whole blood in a first container;
- centrifuging the whole blood into a supernatant component and a sediment component, wherein centrifuging the whole blood comprises positioning the first container containing the whole blood in a centrifuge bucket and positioning a filter assembly comprising a housing and a porous medium on a bracket adapted to receive the filter assembly and carried by the centrifuge bucket;
- removing the supernatant component from the first container;
- and
- passing the sediment component through a porous medium and into another container, wherein the porous medium removes leucocytes from packed red cells and has a CWST of greater than about 53 dynes/cm.
2 more elements
A method for collecting and processing blood comprising:
- collecting whole blood in the first container of a blood collection and processing system comprising a first container for whole blood, a second container for a blood component, and a filter assembly interposed between the first container and the second container;
- placing the first container holding whole blood and the second container in a centrifuge bucket;
- positioning the filter assembly on a bracket away from the bottom of the centrifuge bucket;
- and
- centrifuging the system.
2 more elements
Dependencies are inferred from the claim text.