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US 5,091,525 AGranted
Monohydrate and DMF solvates of a new carbacephem antibiotic
AssigneeEli Lilly and Company
InventorJohn Brennan
Life of this patent
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Abstract
The crystalline monohydrate, mono (N,N'-dimethylformamide) and bis(N,N'-dimethylformamide) solvates of 7.beta.-[2'-(R)-2'-(p-hydroxyphenyl-2'-amino-acetamido]-3-chloro-3-(1-carb adethiacephem)-4-carboxylic acid ("LY213735") are novel compounds with superior physical characteristics. Also described are pharmaceutical formulations of crystalline LY213735 monohydrate.
Claims4
A crystalline mono(N,N'-dimethylformamide) solvate of the compound of the formula ##STR22##
A crystalline bis(N,N'-dimethylformamide) solvate compound of the formula ##STR23##
Dependencies are inferred from the claim text.