Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy

A compound of the formula ##STR13## wherein:

• M is a radionuclide ion, to which one or two oxygen atoms may be bonded:
• R is hydrogen;
• alkyl or geminal dialkyl, wherein said alkyl contains from 1 to 7 carbons;
• or a non-alkyl side chain of a genetically encoded amino acid other than cysteine;
• each X independently represents H.sub.2 or O;
• n is 3 or 4;
• Z is amino;
• a carboxylic ester;
• an imidate ester;
• ##STR14## wherein W.sub.1 is a polypeptide having at least two amino acids;
• ##STR15## wherein W.sub.2 and W.sub.3 independently represents a carbohydrate and the nitrogen is bonded to a carbon atom of W.sub.3.