Removal aid and use thereof

A therapeutic system for transfer of a medicament active substance by skin contact comprising at least one manually detachable therapeutic plaster substrate containing a medicament active substance, said substrate adhering to a sheet-like, flexible carrier material having a contact surface contacting the substrate in the form of predetermined lines of weakness in said carrier material, characterized in that a separate, non-linear, predetermined line of weakness (4) is provided for each said substrate at least in the contact surface of carrier material (1) substantially beneath each said substrate in such a way that when pressure is applied to the carrier material (1) with a force component in a direction at right angles to a corresponding substrate contact surface, it is possible to bend a carrier material portion bounded by the predetermined line of weakness (4) with the substrate portion adhering to it in the direction of the substrate or substrates (2), so that at least part of substrate (2) is detached in its border area adjacent to the predetermined line of weakness (4) from the carrier material (1) and consequently a gripping portion (5) is formed on the substrate for the complete removal of the latter.