US 5,081,304 A · Isotopically-labeled polycyclic amine derivatives

Abstract

A series of isotopically-labeled fluorenamine, dibenzofuranamine, and dibenzothiophenamine derivatives useful for diagnosing neurodegenerative disorders in mammals wherein a detectable amount of an isotope-labeled fluorenamine, dibenzofuranamine, or dibenzothiophenamine derivative is used.

Claims1

Dependent claims

A radioisotopically-labeled compound selected from the group consisting of:

1. 2,3,4,9,9a-hexahydro-(N-ethyl-(2-.sup.11 C))-4aH-fluoren-4a-amine,
(7-fluoro-.sub.18 F)-1,2,3,4,9,9a-hexahydro-N-methyl-4aH-fluoren-4a-amine, and
(7-fluoro-.sub.18 F)-1,4,9,9a-tetrahydro-N-methyl-4aH-fluoren-4a-amine.

Dependencies are inferred from the claim text.

Facts

Application

07/526,486Filed 10 Jul 1990 · division

Priority

22 Sep 1988

Granted

14 Jan 1992

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07C 211/42
Containing condensed ring systems: with six-membered aromatic rings being part of the condensed ring systems
A61K 51/0419
Having oxygen as the only ring hetero atom, e.g. fungichromin: having five-membered rings with one oxygen as the only ring hetero atom, e.g.…
A61K 51/0431
Having sulfur as a ring hetero atom: having five-membered rings
A61K 2123/00
Preparations for testing in vivo

Isotopically-labeled polycyclic amine derivatives

Life of this patent

Abstract

Claims1

Isotopically-labeled polycyclic amine derivatives

Life of this patent

Abstract

Claims1