Alkali-free bioactive sol-gel compositions
AssigneeGeltech, Inc.
InventorsLarry L. Hench, Arthur E. Clark, Rounan Li
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Abstract
Sol-gel processing techniques are used to produce alkali-free bioactive glass compositions based on SiO.sub.2, CaO and P.sub.2 O.sub.5. By varying the SiO.sub.2 content, a range of hydroxyapatite production rates can be obtained; conversely, varying the time of exposure to actual or simulated in vivo solutions permits use of a range of allowable proportions of SiO.sub.2. The sol-gel derived compositions can be chosen to achieve target values for thermal expansion coefficient, elastic modulus and volume electrical resistivity.
Claims6
A bioactive composition prepared using a sol-gel process, and consisting essentially of more than 60 but no more than 86 weight percent SiO.sub.2, at least 4 but less than 33 weight percent CaO and at least 3 but no more than 15 weight percent P.sub.2 O.sub.5.
A bioactive glass powder consisting essentially of SiO.sub.2, CaO and P.sub.2 O.sub.5, prepared using a sol-gel process, and having pores with a diameter range of from about 1.2 to about 10 nm and a surface area of at least 200 m.sup.2 /g, wherein the weight percentage of SiO.sub.2 is more than 60 but no more than 86, the weight percentage of CaO is at least 4 but less than 33, and the weight percentage of P.sub.2 O.sub.5 is at least 3 but no more than 15.
Dependencies are inferred from the claim text.