Method and device for ketone measurement
AssigneeAbbott Laboratories
InventorsSamar K. Kundu, Richard W. George, Steven C. March, Sangvorn Rutnarak
Life of this patent
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Abstract
Methods and materials detect ketone and aldehyde analytes in fluid samples by reacting analyte containing samples with a first solid matrix material to which a nitroprusside salt is coupled and a second solid matrix material to which an amine is covalently coupled. Methods and devices are also provided for ascertaining the fat catabolism effects of a weight loss dietary regimen comprising determining the breath acetone concentration of the subject.
Claims9
A method for ascertaining the fat catabolism effects of a weight loss dietary regimen, said method comprising:
- (a) periodically assaying breath for acetone content, and
- (b) correlating breath acetone content to a standard reflecting the effect on breath acetone of fixed rates of fat catabolism.
A kit for the determination of ketone and aldehyde concentrations in a vapor sample comprising:
- (a) a first solid matrix material to which a nitroprusside salt is coupled,
- (b) a second solid matrix material to which a primary or secondary amine is covalently bound,
- (c) a solvent, and
- (d) means for collecting a fixed volume of sample vapor and contacting it with the first solid matrix material and the second solid matrix material.
A kit for the determination of ketone and aldehyde concentrations in a liquid sample comprising:
- (a) a first solid matrix material to which a nitroprusside salt is coupled,
- (b) a second solid matrix material to which a primary or secondary amine is covalently bound, and
- (c) means for collecting a fixed volume of the liquid sample and contacting it with the first solid matrix material and the second solid matrix material.
A kit for ascertaining the fat catabolism effects of a weight loss dietary regimen comprising:
- (a) a first solid matrix material to which a nitroprusside salt is coupled,
- (b) a second solid matrix material to which a primary or secondary amine is covalently bound,
- (c) a solvent,
- (d) means for collecting a fixed volume of breath and contacting it with the first solid matrix material and the second solid matrix material, and
- (e) a standard reflecting the effect on breath acetone of fixed rates of fat catabolism.
Dependencies are inferred from the claim text.