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US 5,068,236 AGranted
Xanthine derivatives
AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsFumio Suzuki, Junichi Shimada, Kazuhiro Kubo, Tetsuji Ohno, Akira Karasawa, Akio Ishii, Hiromi Nonaka
Life of this patent
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Abstract
Novel xanthine compounds represented by the following formula: ##STR1## and pharmaceutically acceptable salts thereof have a diuretic action, a renal-protecting action and a vasodilative action. The compounds are useful as a diuretic, a renal-protecting agent and an antihypertensive agent.
Claims5
A xanthine compound represented by the following formula:
- ##STR35## wherein each of R.sup.1, R.sup.2 and R.sup.3 independently represents hydrogen or lower alkyl;
- each of R.sup.4 and R.sup.5 independently represents substituted or unsubstituted alicyclic alkyl, and each of X.sup.1 and X.sup.2 independently represents oxygen or sulfur, or its pharmaceutically acceptable salt.
Dependencies are inferred from the claim text.