Process for compacting a calcium phosphate composition
AssigneeRhone-Poulenc Basic Chemicals Co.
InventorThomas W. Gerard
Life of this patent
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Abstract
A process for treating calcium phosphate fine particles which includes the step of compacting the particles under pressure to form a sheet.
Claims10
A mechanical process for treating calcium phosphate fine particles comprising compacting dry-mixed fine particles consisting essentially of calcium phosphate under pressure to form compacted calcium phosphate and comminuting the compacted calcium phosphate to granules suitable for use as an excipient for making pharmaceutical tablets.
A mechanical process for treating fine particles consisting essentially of drymixed calcium phosphate which includes the step of compacting the particles under pressure to form a compacted calcium phosphate followed by the additional step of comminuting said compacted calcium phosphate to granules.
A mechanical process for treating fine particles consisting essentially of drymixed calcium phosphate which includes the step of compacting the particles under pressure to form a compacted calcium phosphate wherein the pressure ranges from about 4,000 to about 18,000 lbs. force per linear inch of roll width in a roller compactor.
A mechanical process for treating fine particles consisting essentially of drymixed calcium phosphate which includes the step of compacting the particles under pressure to form a compacted calcium phosphate wherein the pressure ranges from about 8,000 to about 14,000 lbs. force per linear inch of roll width in a roller compactor.
An improved mechanical process for forming granules from fine particles of calcium phosphate of less than 75 microns comprising compacting in a roller compactor particles consisting essentially of dry mixed calcium phosphate having a particle size of less than about 75 microns under pressure sufficient to form compacted calcium phosphate and comminuting said compacted calcium phosphate to form granules of a particle size larger than 75 microns.
Dependencies are inferred from the claim text.