Amino-esters of dihydropyridines useful for improving circulation in patients
AssigneeBayer Aktiengesellschaft
InventorsEckhard Schwenner, Hartmut Stegelmeier, Stanislav Kazda, Andreas Knorr
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Abstract
Circulation active compounds of the formula ##STR1## in which R.sup.1 is phenyl or heterocyclyl substituted by nitro, trifluoromethyl or other radicals, R.sup.2 is optionally substituted alkyl or other radical R.sup.3 and R.sup.5 are hydrogen, methyl or other radicals, R.sup.4 is hydrogen or optionally substituted alkyl, X is from 2 to 15, and R.sup.6 is ##STR2## and physiologically acceptable salts thereof.
Claims4
An aminoalkyl ester of a dihydropyridinedicarboxylic acid of the formula ##STR45## in which R.sup.1 is phenyl, the phenyl ring being optionally substituted by 1 or 2 identical or different substituents from the group consisting of chlorine, trifluoromethyl, nitro and cyano,
- R.sup.2 is a straight-chain or branched hydrocarbon radical which has up to 7 carbon atoms and is optionally interrupted in the chain by an oxygen atom and said hydrocarbon radical is optionally substituted by fluorine and cyano,
- X is a number from 2 to 6, and
- R.sup.6 represents a radical of the formula ##STR46## wherein R.sup.7 represents hydrogen or methoxy and
- R.sup.8 represents hydrogen, or represents straight-chain or branched C.sub.1 -C.sub.6 -alkyl, or represents the group of the formula ##STR47## or a physiologically acceptable salt thereof.
Dependencies are inferred from the claim text.