Adamantane derivatives in the prevention and treatment of cerebral ischemia
AssigneeMerz + Co. GmbH & Co.
InventorsJoachim Bormann, Markus R. Gold, Wolfgang Schatton
Life of this patent
Estimating the term…
Abstract
A method for the prevention and treatment of cerebral ischemia using an adamantane derivative of the formula ##STR1## wherein R.sub.1 and R.sub.2 are identical or different, representing hydrogen or a straight or branched alkyl group of 1 to 6 C atoms or, in conjunction with N, a heterocyclic group with 5 or 6 ring C atoms; wherein R.sub.3 and R.sub.4 are identical or different, being selected from hydrogen, a straight or branched alkyl group of 1 to 6 C atoms, a cycloalkyl group with 5 or 6 C atoms, and phenyl; wherein R.sub.5 is hydrogen or a straight or branched C.sub.1 -C.sub.6 alkyl group, or a pharmaceutically-acceptable salt thereof, is disclosed.
Claims13
A method for the prevention or treatment of cerebral ischemia comprising the step of administering, to a patient in need thereof, an effective amount of an adamantane derivative of the general formula ##STR5## wherein R.sub.1 and R.sub.2 are identical or different and represent hydrogen or a straight or branched alkyl group of 1 to 6 C atoms or, in conjunction with N, a heterocyclic group with 5 or 6 ring C atoms;
- wherein
- R.sub.3 and R.sub.4 are identical or different, being selected from hydrogen, a straight or branched alkyl group of 1 to 6 C atoms, a cycloalkyl group with 5 or 6 C atoms, and phenyl;
- wherein
- R.sub.5 is hydrogen or a straight or branched C.sub.1 -C.sub.6 alkyl group,
- or a pharmaceutically-acceptable salt thereof.
Dependencies are inferred from the claim text.