Resampling system using data interpolation to eliminate time effects
AssigneeLinear Instruments
InventorsKirk C. Odencrantz, Louis Hlousek, Scot R. Weinberger
Life of this patent
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Abstract
Absorbance and wavelength data which is generated by a liquid chromatography apparatus is orthogonalized and resampled by a cubic splining technique in order to provide a smooth spectra curve showing absorbance versus wavelength, with the time factor eliminated. This has the advantage of eliminating from the data any changes in the sample over time. The method results in the orthogonalization with respect to time of the data. The invention is applicable to analysis of data other than liquid chromatography data. Higher or lower order curve fitting techniques may be used instead of the cubic splining analysis method.
Claims8
A method for collecting and analyzing data comprising the steps of:
- collecting data having at least two variables taken over a discrete time period;
- orthognoalizing a function of a first variable with respect to time for a plurality of values of a second variable wherein the function of the first variable is at a plurality of values of the second variable and the first and second variables are independent to one another;
- interpolating data points of the function of the first variable with respect to time;
- and
- determining a relationship between the first variable and the second variable with respect to time.
An instrument comprising:
- means for collecting data over a period of time having at least two variables;
- means for orthogonalizing a first variable with respect to time for a plurality of values of a second variable wherein the function of the first variable is at a plurality of values of the second variable and the first and second variables are independent to one another;
- means for interpolating data points of the function of the first variable with respect to time;
- and
- means for determining a relationship between the first variable and the second variable with respect to time.
Dependencies are inferred from the claim text.