Compositions containing thymopentin for topical treatment of skin disorders
AssigneeImmunobiology Research Institute, Inc.
InventorsTapan Audhya, Krishnamurthy Venkatasubramanian, Gideon Goldstein
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Abstract
A composition for use in the topical treatment of skin disorders such as dermatitis or poison ivy, which comprises an effective amount of thymopentin and a suitable carrier is provided. A method for treating skin disorders and a method for making a topical composition are disclosed.
Claims26
A therapeutic composition for use in the treatment of a skin disorder comprising an effective amount of thymopentin or an analog thereof in a pharmaceutically acceptable carrier suitable for topical administration directly onto the surface of the skin.
A therapeutic composition for use in the treatment of a skin disorder comprising between about 0.1 to about 10% by weight of thymopentin in a pharmaceutically acceptable carrier suitable for topical administration directly onto the surface of the skin, which carrier consists essentially of about 30% of a fatty acid alcohol;
- about 3 to 4% glycerin;
- about 2-5% detergent;
- about 30 to 35% petroleum jelly;
- about 0 to 2% of a free fatty acid;
- and the balance of water.
A therapeutic composition for use in the treatment of a skin disorder comprising between about 0.1 to about 10% by weight of thymopentin in a pharmaceutically acceptable carrier suitable for topical administration directly onto the surface of the skin, which carrier consists essentially of about 2-7% of a fatty acid alcohol;
- about 1 to 3% glycerin;
- about 5 to 15% mineral oil;
- about 5 to 7% detergent;
- about 0-3% of a free fatty acid;
- about 50-70% purified water;
- about 0 to 10% pH stabilizer, and about 0 to 0.3% preservative.
A therapeutic composition for use in the treatment of a skin disorder consisting essentially of about 10% thymopentin, about 7% of a combination of cetyl and steryl alcohols;
- about 1% glycerin;
- about 15% mineral oil;
- about 50.7% purified water;
- about 10% glycine, about 6% detergents and about 0.3% preservative.
A method for reducing the irritation of a skin disorder comprising administering directly onto a skin disorder of a mammal in need of such treatment, a topical formulation containing an effective amount of thymopentin or an analog thereof in a pharmaceutically acceptable carrier.
A method for the preparation of a topical formulation of thymopentin or an analog thereof comprising distributing evenly throughout an emulsion an effective amount of thymopentin micronized to a high micron size of approximately 2 to 5 microns;
- and providing the composition with a pH of about 7.
Dependencies are inferred from the claim text.