Method and system for producing sterile aqueous solutions

A system for producing USP XXII specifications grade water for injection from a potable water which comprises:

• (a) a filtration means adapted to remove particulate impurities from water;
• (b) an adsorption means containing an adsorbent for removing chlorine and dissolved organics;
• (c) a reverse osmosis separation means adapted to remove organics, dissolved solids, microorganisms and pyrogens from water;
• (d) means for passing the potable water through said filtration means, said adsorption means, said reverse osmosis means and said deionization means;
• and
• (e) means for passing heated water periodically through said filtration means, said adsorption means said reverse osmosis means and said deionization means thereby to flush accumulated pyrogens and to control microorganisms within the said system.

A system for producing USP XXII specifications grade sterile water for injection from a potable water source which comprises:

• (a) a filtration means adapted to remove particulate impurities from water;
• (b) an adsorption means containing an adsorbent for removing chlorine and dissolved organics;
• (c) a reverse osmosis separation means adapted to remove organics, dissolved solids, microorganisms and pyrogens from water;
• (d) sterile microfiltration means downstream of steps (a), (b) and (c) adapted to remove bacteria from water;
• (e) means for passing the potable grade water through said filtration means, said adsorption means, said reverse osmosis separation means and said sterile filtration means;
• and
• (f) means for passing heated water periodically through said filtration means, said adsorption means and said reverse osmosis means thereby to flush accumulated pyrogens and to control microorganisms within the said system.

A system for producing sterile peritoneal dialysis fluid from a potable water source which comprises:

• (a) a filtration means adapted to remove particulate impurities from water;
• (b) an adsorption means containing an adsorbent for removing chlorine and dissolved organics;
• (c) a reverse osmosis separation means adapted to remove organics dissolved solids, microorganisms and pyrogens from water;
• (d) sterile microfiltration means downstream of steps (a), (b), and (c) adapted to remove bacteria from water;
• (e) means for passing the potable grade water through said filtration means, said adsorption means, said reverse osmosis separation means, and said microfiltration means;
• (f) means for proportioning concentrated peritoneal fluids with water exiting said reverse osmosis means and entering said sterile microfiltration means;
• and
• (g) means for passing heated water periodically through said filtration means, said adsorption means, and said reverse osmosis means thereby to flush accumulated pyrogens and to control microorganisms within the said system.

A system for producing sterile medical fluids from a potable water source which comprises:

• (a) a filtration means adapted to remove particulate impurities from water;
• (b) an adsorption means containing an adsorbent for removing chlorine and dissolved organics;
• (c) a reverse osmosis separation means adapted to remove organics, dissolved solids, microorganisms and pyrogens from water;
• (d) sterile microfiltration means downstream of steps (a), (b) and (c) adapted to remove bacteria from water;
• (e) means for passing the potable water through said first filtration means, said reverse osmosis separation means and said sterile microfiltration means;
• (f) means for proportioning concentrated medicament solutions with water exiting said reverse osmosis means and entering said sterile microfiltration means;
• and
• (g) means for passing heated water periodically through said filtration means, said adsorption means and said reverse osmosis means thereby to flush accumulated pyrogens and to control microorganisms within the said system.