Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and a method of nerve regeneration using said conduit
AssigneeColla-Tec Incorporated
InventorShu-Tung Li
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Abstract
The present invention is directed to hollow conduits whose walls are comprised of Type I collagen and are characterized by having a multi-layered, semi-permeable structure, which conduits are used to promote nerve regeneration across a gap of a severed nerve. Methods of making the nerve regeneration conduit are also disclosed.
Claims2
A method of promoting in vivo regeneration of a mammalian severed nerve so as to bridge a gap between its severed ends comprising bringing the respective ends of the severed nerve into contact with each end of a hollow conduit whose walls are comprised of Type I collagen, said walls characterized by having an inner layer communicating with the hollow interior of the conduit having a pore size in the range of from about 0.006 .mu.m to about 5.0 .mu.m and a substantially porous outer layer communicating with the exterior of the conduit.
Dependencies are inferred from the claim text.