Back to results
US 5,015,483 AGranted
Liposome composition for the stabilization of oxidizable substances
AssigneeNabisco Brands, Inc.
InventorsLynn C. Haynes, Harry Levine, John W. Finley
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeNabisco Brands, Inc.
InventorsLynn C. Haynes, Harry Levine, John W. Finley
Estimating the term…
A stable, food-compatible liposome is prepared by dissolving a lipophilic material in a phospholipid followed by the addition of water or an aqueous solution and mixing by sonicating to producing a liposome having the lipophilic material encapsulated in the lipid bilayer. The preferred lipophilic materials include any readily oxidizable lipid and in particular the omega-3 fatty acid containing fish oils. Other lipophilic materials which can be encapsulated in the lipidic bilayer include flavorants, acidulants, preservatives and antioxidants. The resulting liposomes provide a stabilizing vehicle for the lipophilic materials to reduce the occurrence of oxidation and rancidity. Liposomes prepared according to the disclosed method exhibit none of the unpleasant odor and flavor characteristics normally associated with oxidized or rancid oils. The liposomes provide an extended shelf life of the unstable oils and can be added directly to the food product as a dispersion during the manufacturing stage or dried to a free flowing powder for later use.
A shelf-stable, edible liposome composition comprising liposomes having an oxidizable lipophilic material dispersed in the lipid layer of said liposomes providing said lipophilic material with an improved resistance to autoxidation, and wherein said liposomes comprise at least one entrapped aqueous material and at least one polar lipid bilayer, said lipid bilayer including an effective amount of a liposome-forming polar lipid having dispersed therein at least one edible oxidizable lipophilic material.
A stabilized, oxidation-resistant fish oil containing composition comprising liposomes having at least one polar lipid bilayer, and at least one entrapped aqueous material, wherein said lipid bilayer comprises an effective amount of at least one liposome-forming polar lipid and at least one fish oil dispersed in said polar lipid whereby oxidation of said fish oil is inhibited.
A shelf-stable, edible liposome composition containing liposomes having at least one polar lipid bilayer and at least one entrapped aqueous material;
A shelf-stable, edible liposome composition comprising liposomes having at least one lipid bilayer entrapping at least one aqueous material;
Dependencies are inferred from the claim text.