Substituted 4-azatricyclo(22.3.1.0.sup.4,9)octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them

Abstract

The compounds of formula I ##STR1## wherein either R.sub.1 is hydroxy, R.sub.2 is allyl or n-propyl and there is a single bond between the carbon atoms numbered 14 and 15 or R.sub.1 is missing, R.sub.2 is allyl and there is a double bond between the carbon atoms numbered 14 and 15, have interesting immunosuppressant and anti-inflammatory properties. They are obtained by fermentation or synthesis, e.g. by hydrogenation or dehydration.

Dependencies are inferred from the claim text.