Vesicle stabilization
AssigneeVestar, Inc.
InventorGeorge W. Tin
Life of this patent
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Abstract
The present invention relates to a process of stabilizing micellular particles such as vesicles and increasing the shelf life by suspending the particles in a polymeric gel matrix. The invention also relates to such particles suspended in the gel matrix with a protective gel surface thereabout which is capable of becoming fluid and converting the protective surface of an aqueous suspension.
Claims12
A method for the storage and use of small micellular particles, comprising the steps of:
- suspending said micellular particles in a pharmaceutically acceptable polymeric gel solution to form a suspension with a protective gel surface about said micellular particles;
- cooling the suspension to form a gel matrix which restricts movement of the particles;
- and warming the gel matrix to at least about room temperature, thereby transforming the gel matrix into an aqueous suspension suitable for use.
A method for the storage of micellular particles, comprising suspending said micellular particles in a pharmaceutically acceptable polymeric gel solution to form a suspension with a protective gel surface about said micellular particles, said suspension being fluid at room temperature, cooling said suspension to form a gel matrix which restricts movement of said particles, and subsequently warming the gel matrix to at least about room temperature to return the gel matrix to its fluid state.
Dependencies are inferred from the claim text.