Prosthetic meniscus
AssigneeReGen Corporation
InventorKevin R. Stone
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Abstract
A prosthetic, resorbable meniscus and method of its fabrication are disclosed. The prosthetic meniscus can be implanted in a human knee where it can act as a scaffold for regrowth of native meniscal tissues. The meniscus comprises a dry, porous, matrix of biocompatible and bioresorbable fibers, at least a portion of which may be crosslinked. The fibers include natural polymers or analogs or mixtures thereof. The matrix is adapted to have in vivo an outer surface contour substantially the same as that of a natural meniscus. The matrix has pore size in the approximate range of greater than 50 microns to less than about 500 microns. With this configuration, the matrix establishes an at least partially bioresorbable scaffold adapted for ingrowth of meniscal fibrochondrocytes.
Claims34
A prosthetic meniscus comprising a dry porous matrix of biocompatible bioresorbable fibers,
- said fibers selected from the group consisting of natural polymers, and analogs and mixtures thereof,
- said matrix being adapted to have an vivo an outer surface contour substantially the same as that of a natural meniscus,
- said matrix having pore size in the approximate range of greater than 50 microns to less than about 500 microns,
- whereby said matrix establishes an at least partially bioresorbable scaffold adapted for ingrowth of meniscal fibrochondrocytes, and wherein said scaffold and said ingrown meniscal fibrochondrocytes support natural meniscal load forces.
Dependencies are inferred from the claim text.