Carbostyril derivatives
AssigneeOtsuka Pharmaceutical Co., Ltd.
InventorsYasuo Oshiro, Seiji Sato, Nobuyuki Kurahashi
Life of this patent
Estimating the term…
Abstract
A novel carbostyril derivative and salt thereof represented by the formula (1) ##STR1## (wherein R is a group of the formula ##STR2## ((wherein R.sup.1 is a C.sub.1- C.sub.3 alkoxy group)), a group of the formula ##STR3## ((wherein R.sup.2 and R .sup.3 are each, at the same time, a chlorine atom, a bromine atom; and R.sup.4 is a hydrogen atom or a chlorine atom)), 2-methyl-3-nitrophenyl group, 3,5-dichlorophenyl group, or a group of the formula ##STR4## ((wherein R.sup.5 is a chlorine atom or a bromine atom; and R.sup.6 is a methyl group)); the carbon-carbon bond between 3- and 4-position in the carbostyril skeleton is a single or double bond).
Claims21
A carboxtyril compound or salt thereof of the formula, ##STR34## wherein R is a group of the formula ##STR35## wherein R.sup.1 is a C.sub.1 -C.sub.3 alkoxy group;
- a group of the formula ##STR36## wherein R.sup.2 and R.sup.3 are at the same time, both chlorine atoms, or both bromine atoms and R.sup.4 is a hydrogen atom or a chlorine atom;
- a 2-methyl-3-nitrophenyl group;
- a 3,5-dichlorophenyl group;
- or a group of the formula ##STR37## wherein R.sup.5 is a chlorine atom or a bromine atom and R.sup.6 is a methyl group;
- the carbon-carbon bond between the 3- and 4-positions in the carboxtyril skeleton being a single or a double bond.
7-{4-[4-(2,3 -Dichlorophenyl)-1-piperazinyl]butoxy}-3,4-dihydrocarbostyril.
7-{4-[4-(b 2,3-Dichlorophenyl)-1-piperazinyl]-butoxy}carbostyril.
7-{4-[4-(2-Ethoxyphenyl)-1-piperazinyl]butoxy}-3,4-dihydrocarbostyril.
7-{4-[4-]2-Ethoxyphenyl)-1-piperazinyl]butoxy}-carbostyril.
Dependencies are inferred from the claim text.