Back to results
US 5,002,071 AGranted
Injectable soft tissue augmentation materials from the placenta and their method of manufacture
AssigneeResearch Development Foundation
InventorCarl R. Harrell
Life of this patent
Estimating the term…
Abstract
Disclosed is a soft tissue augmentation material from human placenta homogenized to pass through a surgical needle, preferably a 30 gauge surgical needle, and cross-linking collagen molecules of the material by gamma irradiation. Also disclosed are methods of making the injectable soft tissue augmentation material and using it in human beings.
Claims21
An injectable soft tissue augmentation material comprising,
- a sterilized mixture of type I and type III collagen extracted by proteolytic digestion from the group consisting of insoluble amnion, soluble amnion, soluble chorion from human placenta and combinations thereof,
- homogenized to pass through a surgical needle.
The injectable soft tissue augmentation material of claim I where,
- the gamma irradiation is a minimum of 0.20 M rads.
The injectable soft tissue augmentation material of claim I includes,
- an analgesic.
A method of making an injectable soft tissue material comprising,
- sterilizing a mixture of type I and type III collagen extracted by pepsin digestion selected from the group consisting of insoluble amnion, soluble amnion, soluble chorion from human placenta and combinations thereof, and
- homogenizing the material sufficiently to pass through at least a 25 gauge surgical needle.
Dependencies are inferred from the claim text.