6-(disubstituted amino)carbapenem compounds
AssigneeSanraku Incorporated
InventorsTakeo Yoshioka, Noritaka Chida, Azuma Watanabe, Yasuo Fukagawa, Tomoyuki Ishikura
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AssigneeSanraku Incorporated
InventorsTakeo Yoshioka, Noritaka Chida, Azuma Watanabe, Yasuo Fukagawa, Tomoyuki Ishikura
Estimating the term…
A compound represented by the formula ##STR1## wherein R.sub.1 represents a lower alkyl group or a lower haloalkyl group; R.sub.2 represents a lower alkyl group, a lower haloalkyl group, an aralkyl group, or a group of the formula --COOR.sub.4 or --SO.sub.2 R.sub.5 in which R.sub.4 represents an aralkyl group or a substituted or unsubstituted alkyl group and R.sub.5 represents an alkyl group or a substituted or unsubstituted aryl group; and R.sub.3 represents a hydrogen atom or a carboxyl protecting group which can be easily split off. This compound is useful in the production of a 6-(disubstituted amino)carbapenem-series antibiotic. The compounds of the formula ##STR2## wherein R.sub.1 and R.sub.2 are as defined above are important intermediates for the synthesis of the compounds of formula (I) and/or the aforesaid di-(substituted amino) carbapenem-series antibiotics.
A compound of the formula ##STR78## wherein R.sub.1 represents C.sub.1 -C.sub.6 alkyl or C.sub.1 -C.sub.6 haloalkyl, and
Dependencies are inferred from the claim text.